Wits RHI
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IMPOWER-022
IMPOWER-022: A Phase 3 Clinical Study on Oral Islatravir as Preexposure Prophylaxis in Cisgender Women Overview The IMPOWER-022 study is a groundbreaking Phase 3 clinical trial aimed at evaluating the efficacy and safety of oral Islatravir (ISL) administered once monthly (QM) as preexposure prophylaxis (PrEP) for cisgender women at high…
Zoliflodacin Trial
A multi-center, randomized, open-label, noninferiority Trial to evaluate the efficacy and safety of a Single, oral dose of zoliflodacin compared to a Combination of a single intramuscular dose of Ceftriaxone and a single oral dose of azithromycin in the Treatment of patients with uncomplicated gonorrhoea. Rationale There is growing concerns…
PrEP SMART
Evaluation of stepped PrEP adherence support for young South African women using a SMART design. Rationale To evaluate the proportion of young South African women who adhere well to PrEP with regular clinic visits and mHealth interventions alone, the proportion of women who adhere well to PrEP with intensified interventions…
IAVI C100 Study
Safety and Pharmacokinetics of the Combination Broadly Neutralizing Antibodies, 3BNC117- LS-J and 10-1074- LS-J, in Healthy American and African Adults (IAVI C100). Rationale Despite all efforts to increase access to HIV prevention and ART in South Africa, incidence of HIV infection continues to be unacceptably high with an estimated 220…
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Established in 1994, Wits RHI is part of the Faculty of Health Sciences and the largest research institute of the University of the Witwatersrand.
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Hillbrow, 2001
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