Top

CVIA 082 Study

Vaccine Preventable Diseases

A Phase II, Observer-blinded, Randomized, Active-controlled Study to Examine the Immunogenicity and Safety of Rotarix® and RV3-BB when Coadministered/Boosted with Trivalent P2-VP8 Subunit Rotavirus Vaccine Candidate in Healthy Infants in South Africa.

Rationale

Diarrhea is the second-leading cause of infectious disease death worldwide among children under the age of five. Rotavirus is the leading cause of severe diarrhea, resulting in an estimated 215,000 (range: 197,000–233,000) deaths in 2013 which corresponds to 3.4% of all deaths in children.

Investigators

  • Prof Lee Fairlie, Principal Investigator
  • Faeezah Patel
  • Elizea Horne
  • Mrinmayee Dhar

Latest Update

September 2023

For more details about the CVIA 082 Study please email rhicomms@wrhi.ac.za

Research and Policy Briefs

CVIA 082