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PrEP SMART

PrEP SMART: Evaluation of stepped PrEP adherence support for young South African women.

Purpose

To test a stepped model of scalable adherence support strategies in South African young women who initiate PrEP, using a SMART design.

Primary Objectives

To evaluate: the proportion of young South African women who adhere well to PrEP with regular clinic visits and mHealth interventions alone, the proportion of women who adhere well to PrEP with intensified interventions (i.e. monthly visits and special issue counseling or quarterly visits and drug-level feedback), and the optimal sequence of intensifying adherence support among young women who have low adherence after the first two months of use.

Study population

HIV-uninfected women ages 18-25 in Johannesburg, South Africa.

Investigators

  • Sinead Delany-Moretlwe : Protocol Co-Chair

Latest Update:

15 February 2021

For more about PrEP SMART please email rhicomms@wrhi.ac.za

Research and Policy Briefs

Project Brief: PrEP SMART

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